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KMID : 0386319680050010047
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Korean Leprosy Bulletin
1968 Volume.5 No. 1 p.47 ~ p.49
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The Morphological Changes of Mycobacterium Leprae in Culture Media for Tubercle Bacilli
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金在植/Kim, Jae Sik
金源培/徐載柱/河龍馬/金重明/Kim, Won Bae/suh, Jae Joo/Hah, Yong Ma/Kim, Jyung Myung
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Abstract
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Authors observed the morphological changes of Mycobacterium leprae from cultures in Kirchner´s fluid and phosphate buffer solution on every 4th day during 32 days.
On first 4th day, degenerative changes of cells were observed already by formation of granules, elongation,´ swelling and degenerative changes of the cytoplasms.
These changes were developed to marked abnormal features and then gradually to destructions of cells and losses of the characteristics of acid fastness which seems to be in tendency of staining by methylene blue on later day and they gave the similar results on same two media containing antituberculous agents, diaminodiphenylsulfone (25mg.
per ml) and streptomycin (10r. per ml.)
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